Acs Chemical Biology

Probing the Role of Aurora Kinase A Threonylation with Site-Specific Lysine Threonylation

Author: Zang, Jia; Chen, Yulin; Liu, Chao; Lin, Shixian

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. 18, Issue 4, pp. 674-678. DOI: 10.1021/acschembio.1c00682

Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis

Author: Zhou, Zihua; Yang, Xu; Huang, Tingting; Zheng, Jianting; Deng, Zixin; Dai, Shaobo; Lin, Shuangjun

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. 18, Issue 1, pp. 141-150. DOI: 10.1021/acschembio.2c00773

Reversible Redox-Dependent Conformational Switch of the C-Terminal alpha-Helical Lid of Human Hsp70 Observed by In-Cell NMR

Author: Liang, Qihui; Zhang, Yiying; Zhang, Hong; Wu, Si; Gong, Weibin; Perrett, Sarah

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. 18, Issue 1, pp. 176-183. DOI: 10.1021/acschembio.2c00845

Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells

Author: Liu, Yue; Liu, Jiacong; Zhang, Xianfang; Guo, Cuiping; Zhang, Zhi-Min; Xing, Xiwen; Ding, Ke; Li, Zhengqiu

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. 18, Issue 1, pp. 112-122. DOI: 10.1021/acschembio.2c00740

Host-Selective Phytotoxins Incorporating the Epoxy-Triene- Decacarboxylate Moiety Function through the Hijacking of the Plant-Microbe Interaction System

Author: Ueda, Minoru; Kato, Nobuki; Kurata, Yoshinori; Imai, Masaki; Yang, Gangqiang; Taniguchi, Keigo

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. 18, Issue 1, pp. 12-17. DOI: 10.1021/acschembio.2c00777

Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction

Author: Ding, Jian; Li, Guo; Liu, Hejun; Liu, Lulu; Lin, Ying; Gao, Jingyan; Zhou, Guoqiang; Shen, Lingling; Zhao, Mengxi; Yu, Yanyan; Guo, Weihui; Hommel, Ulrich; Ottl, Johannes; Blank, Jutta; Aubin, Nicola; Wei, Yi; He, Hu; Sage, David R.; Atadja, Peter W.; Li, En; Jain, Rishi K.; Tallarico, John A.; Canham, Stephen M.; Chiang, Ying-Ling; Wang, He

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. 18, Issue 1, pp. 34-40. DOI: 10.1021/acschembio.2c00843

Structure-Based Mechanistic Insights into ColB1, a Flavoprotein Functioning in-trans in the 2,2 '-Bipyridine Assembly Line for Cysteine Dehydrogenation

Author: Ma, Xueyang; Tang, Zhijun; Ding, Wenping; Liu, Tan; Yang, Donghui; Liu, Wen; Ma, Ming

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acschembio.2c00785

Optimization of PROTAC Ternary Complex Using DNA Encoded Library Approach

Author: Chen, Qiuxia; Liu, Chuan; Wang, Wei; Meng, Xiaoyun; Cheng, Xuemin; Li, Xianyang; Cai, Longying; Luo, Linfu; He, Xu; Qu, Huan; Luo, Jing; Wei, Hong; Gao, Sen; Liu, Guansai; Wan, Jinqiao; Israel, David I.; Li, Jin; Dou, Dengfeng

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acschembio.2c00797

Guvermectin Biosynthesis Revealing the Key Role of a Phosphoribohydrolase and Structural Insight into the Active Glutamate of a Noncanonical Adenine Phosphoribosyltransferase

Author: Liu, Chongxi; Wang, Zhiyan; Chen, Yin; Yan, Yijun; Li, Lei; Wang, Yong-Jiang; Bai, Lu; Li, Shanshan; Zhang, Yanyan; Wang, Xiangjing; Huang, Sheng-Xiong; Xiang, Wensheng

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acschembio.2c00739

Unexploited Performance of NLS in the dCas9-VPR-Mediated Transcriptional Activation

Author: Zhou, Junxiang; He, Miao; Yin, Xue; Yu, Yue; Yao, Dongbao; Liang, Haojun

Journal: ACS CHEMICAL BIOLOGY. 2023; Vol. , Issue , pp. -. DOI: 10.1021/acschembio.3c00195

Playing with the Molecules of Life

引用次数：38

SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate

引用次数：26

Directed Evolution of Split APEX2 Peroxidase

引用次数：23

Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders

引用次数：20

Design and Characterization of SGK3-PROTAC an Isoform Specific SGK3 Kinase PROTAC Degrader

引用次数：17

Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader

引用次数：16

Dual Allosteric Inhibition of SHP2 Phosphatase

引用次数：16

Genetic Code Expansion in Animals

引用次数：15

Fluorescent Chemosensors as Future Tools for Cancer Biology

引用次数：14

Norbornene Probes for the Detection of Cysteine Sulfenic Acid in Cells

引用次数：13